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Experts warn that: Tariffs on APIs and finished generics could disrupt supply chains Cost increases could force smaller generic manufacturers to exit the U.S

By delaying gastric emptying and slowing intestinal transit time, the medication can disrupt this process, leading to inconsistent bowel movements

[18] Cellular senescence is suspected to be a central contributing cause, a belief which is supported by benefits seen in patients given senolytic therapy

KoopmanWJNijtmansLGDieterenCERoestenbergPValsecchiFSmeitinkJAet alMammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation